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I'm reading: Protein key to brain diseases

Protein key to brain diseases

A protein complex plays a key role in preventing the build-up of toxic plaques in the brain linked to neurodegenerative disorders such as Alzheimer’s and Huntington’s disease, according to new research.

Alzheimer’s and Huntington’s are linked to proteins that “clump together” in brain cells, causing progressive dysfunction and death of the cells. Working with international colleagues, Leeds researchers discovered that the nascent polypeptide-associated complex (NAC) helps prevent this happening. Professor Sheena Radford FRS, who led the Leeds team, said: “By understanding the mechanism of how NAC works, we are closer to developing a molecule to slow down or even prevent degenerative diseases.”